| Drug General Information |
| Drug ID |
D08LFC
|
| Former ID |
DNC014555
|
| Drug Name |
CGP-35024
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C4H12NO2P
|
| InChI |
InChI=1S/C4H12NO2P/c1-8(6,7)4-2-3-5/h2-5H2,1H3,(H,6,7)
|
| InChIKey |
NHVRIDDXGZPJTJ-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
5608484, 7978903, 8153213, 11110690, 11113473, 15219048, 25746534, 26751694, 29224286, 47216900, 47365331, 47662433, 47885537, 48185114, 50064309, 50104385, 53786182, 57322666, 77292575, 85208918, 90513940, 103065080, 103080796, 103334994, 104308634, 117626404, 117733988, 124749445, 124879060, 124879061, 124879062, 124879063, 125660989, 128704542, 131751337, 134224389, 134351760, 135081534, 135649731, 137008675, 140384422, 162223784, 164848763, 166270618, 179148822, 179419315, 204360310, 224018692, 226677152, 241181641
|
| Target and Pathway |
| Target(s) |
Gamma-aminobutyric acid B receptor |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
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cAMP signaling pathway
|
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Neuroactive ligand-receptor interaction
|
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GABAergic synapse
|
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Estrogen signaling pathway
|
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Morphine addiction
|
|
Reactome
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Activation of G protein gated Potassium channels
|
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G alpha (i) signalling events
|
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Class C/3 (Metabotropic glutamate/pheromone receptors)
|
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Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
|
|
WikiPathways
|
GPCRs, Class C Metabotropic glutamate, pheromone
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Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
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Potassium Channels
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GPCR ligand binding
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GPCR downstream signaling
|
| References |
| REF 1 | Biological activity of 3-aminopropyl (methyl) phosphinic acid, a potent and selective GABAB agonist with CNS activity, Bioorg. Med. Chem. Lett. 3(4):515-518 (1993). |
|---|
