Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08MKF
|
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| Former ID |
DNC001017
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| Drug Name |
Nickel chloride
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
Cl2Ni
|
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| Canonical SMILES |
Cl[Ni]Cl
|
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| InChI |
1S/2ClH.Ni/h2*1H;/q;;+2/p-2
|
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| InChIKey |
QMMRZOWCJAIUJA-UHFFFAOYSA-L
|
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| CAS Number |
CAS 7718-54-9
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
138091, 599833, 6718687, 8167797, 10535469, 15995108, 24434799, 24860636, 24868610, 29291457, 49997313, 53787722, 56370154, 57331687, 74788158, 91693525, 104359844, 125824411, 134340282, 134989178, 137005957, 142398023, 144212492, 162240580, 162271138, 162509726, 164779286, 164779295, 176258544, 204363565, 223719324, 223752703
|
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| ChEBI ID |
ChEBI:34887
|
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| Target and Pathway | |||||
| Target(s) | Voltage-dependent T-type calcium channel alpha-1G subunit | Target Info | Blocker | [1] | |
| KEGG Pathway | MAPK signaling pathway | ||||
| Calcium signaling pathway | |||||
| Circadian entrainment | |||||
| Type II diabetes mellitus | |||||
| PANTHER Pathway | Endogenous cannabinoid signaling | ||||
| GABA-B receptor II signaling | |||||
| Nicotine pharmacodynamics pathway | |||||
| Pathway Interaction Database | Regulation of nuclear beta catenin signaling and target gene transcription | ||||
| PathWhiz Pathway | Muscle/Heart Contraction | ||||
| Reactome | NCAM1 interactions | ||||
| WikiPathways | NCAM signaling for neurite out-growth | ||||
| Nicotine Activity on Chromaffin Cells | |||||
| References | |||||
| REF 1 | T-type calcium channels facilitate insulin secretion by enhancing general excitability in the insulin-secreting beta-cell line, INS-1. Endocrinology. 1997 Sep;138(9):3735-40. | ||||
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