Drug General Information
Drug ID
D08MRN
Former ID
DAP000506
Drug Name
Hexylcaine
Synonyms
Hexilcaina; Hexylcainum; Osmocaine; Hexylcaine [INN]; Cyclaine (TN); Hexilcaina [INN-Spanish]; Hexylcainum [INN-Latin]; Osmocaine (TN); (2-Cyclohexylamino-1-methylethyl) benzoate; 1-(Cyclohexylamino)-2-propanol benzoate (ester); 1-(cyclohexylamino)propan-2-yl benzoate; 2-Propanol, 1-(cyclohexylamino)-, benzoate (ester)
Drug Type
Small molecular drug
Indication Local anaesthetic [ICD10:R20.0] Approved [551871]
Anesthesia [ICD9: 338; ICD10:R20.0] Withdrawn from market [538409], [542208]
Therapeutic Class
Anesthetics
Company
Merck & Co
Structure
Download
2D MOL

3D MOL

Formula
C16H23NO2
InChI
InChI=1S/C16H23NO2/c1-13(12-17-15-10-6-3-7-11-15)19-16(18)14-8-4-2-5-9-14/h2,4-5,8-9,13,15,17H,3,6-7,10-12H2,1H3
InChIKey
DKLKMKYDWHYZTD-UHFFFAOYSA-N
CAS Number
CAS 532-77-4
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Sodium channel protein type 5 subunit alpha Target Info Blocker [536316]
KEGG Pathway Adrenergic signaling in cardiomyocytes
PathWhiz Pathway Muscle/Heart Contraction
Reactome Interaction between L1 and Ankyrins
WikiPathways SIDS Susceptibility Pathways
Cardiac Progenitor Differentiation
References
Ref 538409FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 008472.
Ref 542208(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7196).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536316How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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