Drug General Information
Drug ID	D08NRG
Former ID	DIB008656
Drug Name	HYP-10
Synonyms	T-type calcium channel blockers (pain), Ewha Woman's University
Indication	Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89]		Investigative	[543872]
Company	Ewha Woman's University
Structure		Download 2D MOL 3D MOL
Canonical SMILES	C(=O)(CCCN)N1CCN(CC1)C(c1ccccc1)c1ccc(cc1)Cl
Target and Pathway
Target(s)	Voltage-dependent T-type calcium channel subunit alpha-1H	Target Info	Blocker	[543872]
KEGG Pathway	MAPK signaling pathway
	Calcium signaling pathway
	Circadian entrainment
PathWhiz Pathway	Muscle/Heart Contraction
Reactome	NCAM1 interactions
WikiPathways	Corticotropin-releasing hormone
	NCAM signaling for neurite out-growth
References
Ref 543872	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 536).
Ref 543872	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 536).

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