Drug Information
Drug General Information | |||||
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Drug ID |
D08PIK
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Former ID |
DIB005985
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Drug Name |
11C-GSK-215083
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Synonyms |
11C-5-HT 6 receptor antagonist (neurodegenerative disease), GlaxoSmithKline; 11C-GSK-215083 PET maging agent (neurodegenerative disease), GlaxoSmithKline
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Company |
GlaxoSmithKline plc
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Structure |
Download2D MOL |
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InChI |
InChI=1S/C20H20FN3O2S/c1-23-8-10-24(11-9-23)19-7-2-4-15-12-18(14-22-20(15)19)27(25,26)17-6-3-5-16(21)13-17/h2-7,12-14H,8-11H2,1H3/i1-1
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InChIKey |
PXVJEDOZGDZJQY-BJUDXGSMSA-N
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Target and Pathway | |||||
Target(s) | 5-hydroxytryptamine 6 receptor | Target Info | Antagonist | [531758] | |
PathWhiz Pathway | Excitatory Neural Signalling Through 5-HTR 6 and Serotonin | ||||
References | |||||
Ref 525385 | List of drugs in development for neurodegenerative diseases: update October 2011. Neurodegener Dis. 2012;9(4):210-83. | ||||
Ref 543132 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8430). |
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