Drug Information

Drug General Information
Drug ID
D08TRD
Former ID
DIB020004
Drug Name
hexocyclium
Synonyms
Tral
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540205]
Structure
Download
2D MOL
Formula
C20H33N2O+
InChI
InChI=1S/C20H33N2O/c1-22(2)15-13-21(14-16-22)17-20(23,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3,5-6,9-10,19,23H,4,7-8,11-17H2,1-2H3/q+1
InChIKey
ZRYHPQCHHOKSMD-UHFFFAOYSA-N
PubChem Compound ID
24199
PubChem Substance ID
10013, 5116910, 7979534, 8167667, 29291286, 50679656, 57331623, 85229920, 104359687, 124968854, 129946543, 131342533, 134986545, 135051351, 135650349, 137127666, 179225805, 223439937, 227196344
Target and Pathway
Target(s) Muscarinic acetylcholine receptor M1 Target Info Modulator
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
PI3K-Akt signaling pathway
Cholinergic synapse
Regulation of actin cytoskeleton
PANTHER Pathway Alzheimer disease-amyloid secretase pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Reactome Muscarinic acetylcholine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
Regulation of Actin Cytoskeleton
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
GPCR ligand binding
GPCR downstream signaling
References
Ref 540205(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 323).

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