Drug Information

Drug General Information
Drug ID
D08UOW
Former ID
DIB020385
Drug Name
MMPIP
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540300]
Structure
Download
2D MOL
Formula
C19H15N3O3
InChI
InChI=1S/C19H15N3O3/c1-22-15(12-3-5-14(24-2)6-4-12)11-16-17(19(22)23)18(21-25-16)13-7-9-20-10-8-13/h3-11H,1-2H3
InChIKey
PDWYBOZNEVALOV-UHFFFAOYSA-N
PubChem Compound ID
9945530
PubChem Substance ID
14919986, 24216816, 77795953, 99300377, 103717392, 104160238, 134931879, 137009420, 139126037, 151991291, 162248974, 163108970, 170485580, 172096399, 178100371, 196376170, 229069335, 247578972
Target and Pathway
Target(s) Metabotropic glutamate receptor 7 Target Info Modulator (allosteric modulator) [530592]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Metabotropic glutamate receptor group III pathway
Reactome G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
GPCR ligand binding
GPCR downstream signaling
References
Ref 540300(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3341).
Ref 530592Context-dependent pharmacology exhibited by negative allosteric modulators of metabotropic glutamate receptor 7. Mol Pharmacol. 2010 Mar;77(3):459-68.

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