Drug Information

Drug General Information
Drug ID
D08VXF
Former ID
DNC012231
Drug Name
Cyclohexyl-(9-methyl-9H-purin-6-yl)-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529774]
Structure
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2D MOL

3D MOL
Formula
C12H17N5
Canonical SMILES
CN1C=NC2=C1N=CN=C2NC3CCCCC3
InChI
1S/C12H17N5/c1-17-8-15-10-11(13-7-14-12(10)17)16-9-5-3-2-4-6-9/h7-9H,2-6H2,1H3,(H,13,14,16)
InChIKey
YWCWGJZQICOVCA-UHFFFAOYSA-N
PubChem Compound ID
15693939
Target and Pathway
Target(s) Adenosine A1 receptor Target Info Inhibitor [529774]
KEGG Pathway cGMP-PKG signaling pathway
cAMP signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
Morphine addiction
NetPath Pathway TCR Signaling Pathway
RANKL Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 529774J Med Chem. 1991 Sep;34(9):2877-82.N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor.
Ref 529774J Med Chem. 1991 Sep;34(9):2877-82.N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor.

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