Drug General Information
Drug ID
D08WQM
Former ID
DNC002796
Drug Name
O-Sialic Acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551374]
Structure
Download
2D MOL

3D MOL

Formula
C11H19NO9
Canonical SMILES
CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)O)O
InChI
1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11?/m0/s1
InChIKey
SQVRNKJHWKZAKO-LUWBGTNYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) P-selectin Target Info Inhibitor [551374]
Neuraminidase Target Info Inhibitor [551374]
E-selectin Target Info Inhibitor [551374]
Liver carboxylesterase Target Info Inhibitor [551374]
KEGG Pathway Cell adhesion molecules (CAMs)
Malaria
Staphylococcus aureus infectionstm00511:Other glycan degradationhsa04514:Cell adhesion molecules (CAMs)
TNF signaling pathway
African trypanosomiasis
Malariahsa00983:Drug metabolism - other enzymes
Metabolic pathways
NetPath Pathway IL5 Signaling Pathway
IL4 Signaling Pathway
TNFalpha Signaling Pathway
ID Signaling Pathway
Pathway Interaction Database IL4-mediated signaling events
amb2 Integrin signalingtxa2pathway:Thromboxane A2 receptor signaling
Glucocorticoid receptor regulatory network
ATF-2 transcription factor networke2f_pathway:E2F transcription factor network
Reactome Platelet degranulation
Cell surface interactions at the vascular wallR-HSA-202733:Cell surface interactions at the vascular wall
WikiPathways Human Complement System
Spinal Cord Injury
Cell surface interactions at the vascular wallWP2806:Human Complement System
TNF alpha Signaling Pathway
Cell surface interactions at the vascular wallWP2884:NRF2 pathway
Nuclear Receptors Meta-Pathway
Heroin metabolism
Irinotecan Pathway
Fluoropyrimidine Activity
Phase I biotransformations, non P450
References
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.