Drug Information
Drug General Information | |||||
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Drug ID |
D08XKL
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Former ID |
DIB013558
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Drug Name |
SPI-014
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Synonyms |
SPI-1802; SPI-1810; Amyloid beta peptide 1-42 deposition inhibitor (AD), Satori; Gamma-secretase modulators (Alzheimers disease), Satori Pharmaceuticals
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Indication | Alzheimer disease [ICD9: 331; ICD10:G30] | Phase 1 | [523843] | ||
Company |
Satori Pharmaceuticals Inc
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Structure |
Download2D MOL |
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Target and Pathway | |||||
Target(s) | Gamma-secretase | Target Info | Modulator | [532197] | |
KEGG Pathway | Notch signaling pathway | ||||
Alzheimer's disease | |||||
Reactome | Nuclear signaling by ERBB4 | ||||
Regulated proteolysis of p75NTR | |||||
NRIF signals cell death from the nucleus | |||||
Activated NOTCH1 Transmits Signal to the Nucleus | |||||
Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
NOTCH2 Activation and Transmission of Signal to the Nucleus | |||||
EPH-ephrin mediated repulsion of cells | |||||
References |
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