Drug Information

Drug General Information
Drug ID
D08ZEB
Former ID
DAP000952
Drug Name
Chlorzoxazone
Synonyms
Biomioran; CLW; Chloroxazone; Chlorsoxazone; Chlorzoxane; Chlorzoxazon; Chlorzoxazona; Chlorzoxazonum; Clorzoxazona; Escoflex; Klorzoxazon; Mioran; Miotran; Myoflexin; Myoflexine; Neoflex; Nyoflex; Paraflex; Parafon; Pathorysin; Relaxazone; Remofleks; Remular; Solaxin; Component of Parafon Forte; McNeil Brand of Chlorzoxazone; Ortho Brand of Chlorzoxazone; Parafon Forte; Parafon Forte DSC; Strifon Forte Dsc; C 4397; Chlorzoxazonum [INN-Latin]; Clorzoxazona [INN-Spanish]; EZE-DS; Muscol (TN); Paraflex (TN); Parafon Forte (TN); Remular-S; Usaf ma-10; Chlorzoxazone [INN:BAN:JAN]; Chlorzoxazone (JAN/USP/INN); 2-Hydroxy-5-chlorobenzoxazole; 5-Chlorbenzoxazolin-2-on; 5-Chloro-1,3-benzoxazol-2(3H)-one; 5-Chloro-2(3H)-benzoxazolone; 5-Chloro-2-benzoxazolinone; 5-Chloro-2-benzoxazolol; 5-Chloro-2-benzoxazolone; 5-Chloro-2-hydroxybenzoxazole; 5-Chloro-3(H)-2-benzoxazolone; 5-Chlorobenzoksazolinon-2; 5-Chlorobenzoksazolinon-2 [Polish]; 5-Chlorobenzoksazolon-2; 5-Chlorobenzoksazolon-2 [Polish]; 5-Chlorobenzoxazol-2-one; 5-Chlorobenzoxazolidone; 5-Chlorobenzoxazolone; 5-chloro-1,3-benzoxazol-2-ol; 5-chloro-3H-1,3-benzoxazol-2-one; 5-chlorobenzoxazolin-2-one
Drug Type
Small molecular drug
Indication Acute pain [ICD9: 338,780; ICD10:R52, G89] Approved [538167], [539469], [551871]
Therapeutic Class
Analgesics
Structure
Download
2D MOL

3D MOL
Formula
C7H4ClNO2
InChI
InChI=1S/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10)
InChIKey
TZFWDZFKRBELIQ-UHFFFAOYSA-N
CAS Number
CAS 95-25-0
PubChem Compound ID
2733
PubChem Substance ID
10133, 87091, 826390, 826422, 3139748, 6867174, 7767972, 7847836, 7886649, 8139927, 8149257, 8151769, 10321163, 10538622, 11110945, 11110946, 11336070, 11361309, 11363042, 11365604, 11368166, 11371339, 11373953, 11376328, 11462281, 11466191, 11467311, 11484813, 11485682, 11488965, 11490166, 11492102, 11493962, 16935856, 17404816, 24277702, 26611661, 26679366, 26747469, 26747470, 29221889, 46507755, 47291196, 47662345, 47736550, 47810813, 47959818, 48035200, 48334567, 48334568
SuperDrug ATC ID
M03BB03
SuperDrug CAS ID
cas=000095250
Target and Pathway
Target(s) Calcium-activated potassium channel Target Info Activator [536253]
References
Ref 538167FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 040113.
Ref 539469(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2322).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536253Chlorzoxazone inhibits contraction of rat thoracic aorta. Eur J Pharmacol. 2006 Sep 18;545(2-3):161-6. Epub 2006 Jun 29.

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