Drug General Information
Drug ID
D09AMZ
Former ID
DAP000597
Drug Name
Enprofylline
Synonyms
Enprofilina; Enprofyllinum; Nilyph; Oxeze; P 5679; D-4028; Enprofilina [INN-Spanish]; Enprofylline [USAN:INN]; Enprofyllinum [INN-Latin]; Enprofylline (USAN/INN); 3,7-Dihydro-3-propyl-1H-purine-2,6-dione; 3-Propyl-3,7-dihydro-purine-2,6-dione; 3-Propylxanthine; 3-n-Propylxanthine; 3-propyl-3,7-dihydro-1H-purine-2,6-dione; 3-propyl-7H-purine-2,6-dione
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Approved [537725]
Therapeutic Class
Antiinflammatory Agents
Structure
Download
2D MOL

3D MOL

Formula
C8H10N4O2
Canonical SMILES
CCCN1C2=C(C(=O)NC1=O)NC=N2
InChI
1S/C8H10N4O2/c1-2-3-12-6-5(9-4-10-6)7(13)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,13,14)
InChIKey
SIQPXVQCUCHWDI-UHFFFAOYSA-N
CAS Number
CAS 41078-02-8
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) CAMP-specific 3',5'-cyclic phosphodiesterase 4A Target Info Inhibitor [537725]
KEGG Pathway Purine metabolism
cAMP signaling pathway
Morphine addiction
Reactome DARPP-32 events
G alpha (s) signalling events
WikiPathways G Protein Signaling Pathways
References
Ref 537725Effects of enprofylline, a new xanthine derivate, on human pregnant myometrium. Am J Obstet Gynecol. 1987 Apr;156(4):958-62.
Ref 537725Effects of enprofylline, a new xanthine derivate, on human pregnant myometrium. Am J Obstet Gynecol. 1987 Apr;156(4):958-62.

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