Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09DDQ
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| Former ID |
DIB014502
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| Drug Name |
FUB-130
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| Synonyms |
FUB-130; FUB-132; FUB-250; FUB-465; FUB-86; UCL-1860; UCL-2065; UCL-2283; H3 antagonists, Bioprojet/Berlin Free University/INSERM/UCL
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| Drug Type |
Small molecular drug
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| Indication | Neurological disease [ICD9: 338, 338.2, 410, 782.3,780; ICD10:I21, I22, R52, R52.1-R52.2, R60.9, G89] | Investigative | [1] | ||
| Company |
BioProjet; Societe Civile de Recherche
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| Structure |
|
Download2D MOL |
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| Formula |
C8H14N2O
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| InChI |
InChI=1S/C8H14N2O/c1-2-11-5-3-4-8-6-9-7-10-8/h6-7H,2-5H2,1H3,(H,9,10)
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| InChIKey |
RSHKAUMLIJVWFJ-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Histamine H3 receptor | Target Info | Antagonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Histamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1260). | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264). | ||||
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