Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09KRH
|
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| Former ID |
DIB019775
|
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| Drug Name |
domoic acid
|
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| Synonyms |
domoate; NSC 288031
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C15H21NO6
|
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| InChI |
InChI=1S/C15H21NO6/c1-8(4-3-5-9(2)14(19)20)11-7-16-13(15(21)22)10(11)6-12(17)18/h3-5,9-11,13,16H,6-7H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)/b5-3+,8-4-/t9-,10+,11-,13+/m1/s1
|
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| InChIKey |
VZFRNCSOCOPNDB-AOKDLOFSSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID |
586321, 7887137, 8616969, 14719311, 24894006, 26751666, 26758635, 39315722, 50038062, 57358598, 78284545, 85788985, 91696040, 113856771, 117682352, 123092445, 124812230, 134221965, 135057153, 137242511, 162022521, 163688206, 175607738, 176265315, 178101000, 179316856, 198954949, 223442148, 226717272, 241181599, 241376073, 250134635, 252553471
|
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| Target and Pathway | |||||
| Target(s) | GluK2 | Target Info | Agonist | [2] | |
| Glutamate receptor, ionotropic kainate 1 | Target Info | Agonist | [3] | ||
| GluK4 | Target Info | Agonist | [4] | ||
| GluK5 | Target Info | Agonist | [5] | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Glutamatergic synapse | |||||
| PANTHER Pathway | Huntington disease | ||||
| Ionotropic glutamate receptor pathway | |||||
| Metabotropic glutamate receptor group III pathway | |||||
| Metabotropic glutamate receptor group I pathway | |||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4181). | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 451). | ||||
| REF 3 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 450). | ||||
| REF 4 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 453). | ||||
| REF 5 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 454). | ||||
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