Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09NAW
|
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| Former ID |
DIB001866
|
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| Drug Name |
PF-05105679
|
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| Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Phase 1 | [1] | ||
| Company |
Pfizer Inc
|
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| Structure |
|
Download2D MOL |
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| Target and Pathway | |||||
| Target(s) | TRPM8 protein | Target Info | Modulator | [1] | |
| KEGG Pathway | Inflammatory mediator regulation of TRP channels | ||||
| Reactome | TRP channels | ||||
| References | |||||
| REF 1 | Inhibition of TRPM8 channels reduces pain in the cold pressor test in humans. J Pharmacol Exp Ther. 2014 Nov;351(2):259-69. | ||||
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