Drug Information

Drug General Information
Drug ID
D09PUL
Former ID
DAP000805
Drug Name
L-Alanine
Synonyms
ALA; Alanina; Alanine; Alaninum; LPG; Polyalanine; Alaninum [Latin]; A-Alanine; A-Aminopropionic acid; Alanina [DCIT,Spanish]; Alanine (USP); Alanine (VAN); Alanine [USAN:INN]; Alpha-Alanine; Alpha-Aminopropionic acid; L-Alanin; H-Ala-OH; L-2-Aminopropanoic acid; L-2-Aminopropionic acid; L-2-Aminopropionsaeure; L-A-Aminopropionicacid; L-Alanine (9CI); L-Alanine (JAN); L-Alanine, homopolymer; L-Alanine, labeled with tritium; L-S-Aminopropionic acid; L-a-Alanine; L-a-Aminopropionic acid; L-alpha-Aminopropionic acid; L-alpha-alanine; Poly-DL-alanine; Poly-L-alanine; L-&alpha-alanine; L-Alanine, labeled with carbon-14; Alanine, L-(7CI,8CI); F4F207FF-8FF8-4789-99A1-147AE0A36673; L-(+)-Alanine; L-Alanine, N-coco alkyl derivs.;Propanoic acid, 2-amino-, (S); (2S)-2-Aminopropanoic acid; (C14)L-Alanine; (L)-Alanine; (S)-(+)-Alanine; (S)-2-Aminopropanoic acid; (S)-2-Aminopropionic acid; (S)-2-Aminopropionsaeure; (S)-Alanine; (S)-alpha-Aminopropionsaeure; 14C-L-Alanine; 2-Aminopropionic acid
Drug Type
Small molecular drug
Indication Dietary shortage; Glioma [ICD9: 260-269, 191; ICD10:E40-E46, C71] Approved [542213], [550116], [551871]
Therapeutic Class
Dietary supplement
Structure
Download
2D MOL

3D MOL
Formula
C3H7NO2
InChI
InChI=1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1
InChIKey
QNAYBMKLOCPYGJ-REOHCLBHSA-N
CAS Number
CAS 56-41-7
PubChem Compound ID
5950
PubChem Substance ID
3343, 585842, 589753, 627087, 822335, 841591, 3131856, 6436532, 7847080, 7885836, 7888688, 8144737, 8153694, 10527484, 11113404, 11528607, 14710664, 14720011, 14747373, 24845820, 24890849, 24891241, 24891260, 24901893, 29224973, 46504866, 46508779, 49655376, 56437668, 57323073, 57580857, 78123937, 85164877, 85230829, 85239779, 87350317, 87561861, 92297527, 92719579, 96100165, 96100173, 99224270, 99246016, 103059020, 103059733, 103182286, 103827139, 103914796, 104234104, 104310701
ChEBI ID
ChEBI:16977
Target and Pathway
Target(s) 4-aminobutyrate aminotransferase, mitochondrial Target Info Inhibitor [536555]
BioCyc Pathway GABA shunt
Valine degradation
Beta-alanine degradation
4-aminobutyrate degradation
KEGG Pathway Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine degradation
beta-Alanine metabolism
Propanoate metabolism
Butanoate metabolism
Metabolic pathways
GABAergic synapse
PANTHER Pathway Aminobutyrate degradation
Pyrimidine Metabolism
Gamma-aminobutyric acid synthesis
PathWhiz Pathway Aspartate Metabolism
Glutamate Metabolism
Beta-Alanine Metabolism
Valine, Leucine and Isoleucine Degradation
Propanoate Metabolism
WikiPathways GABA synthesis, release, reuptake and degradation
Alanine and aspartate metabolism
References
Ref 542213(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 720).
Ref 550116Drug information of L-Alanine, Health Canada, 2008. (drugid: 7638)
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536555DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29.

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