TTD | Drug: D09RGZ

Drug General Information
Drug ID	D09RGZ
Former ID	DIB021136
Drug Name	Up3U
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539103]
Structure		Download 2D MOL
Formula	C18H22N4O20P3-3
InChI	InChI=1S/C18H25N4O20P3/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(39-15)5-37-43(31,32)41-45(35,36)42-44(33,34)38-6-8-12(26)14(28)16(40-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,19,23,29)(H,20,24,30)/p-3/t7-,8+,11+,12-,13?,14?,15-,16-/m1/s1
InChIKey	JPNWHMPVXHYIKN-VRXVDWQRSA-K
PubChem Compound ID	73755005
PubChem Substance ID	135651589
Target and Pathway
Target(s)	P2Y purinoceptor 6	Target Info	Agonist	[528028]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	G alpha (q) signalling events
Reactome	P2Y receptors
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539103	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1751).
Ref 528028	P2 receptors activated by uracil nucleotides--an update. Curr Med Chem. 2006;13(3):289-312.

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Drug Information