Drug General Information
Drug ID	D09ROG
Former ID	DNC009091
Drug Name	UCL-2138
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[1]
Structure		Download 2D MOL 3D MOL
Formula	C15H20N2O
InChI	InChI=1S/C15H20N2O/c16-13-14-5-7-15(8-6-14)18-12-4-11-17-9-2-1-3-10-17/h5-8H,1-4,9-12H2
InChIKey	RHMNKKOAWUCDRK-UHFFFAOYSA-N
PubChem Compound ID	2994072
PubChem Substance ID	7340828, 10030917, 14847556, 34660349, 48253940, 48329037, 77004567, 85225741, 103361365, 104023960, 111592614, 129130079, 134346296, 135649791, 137014321, 141397265, 143179198, 145752145, 162400864, 162416673, 169436088, 226807395
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Inhibitor	[2]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
REF 1	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1257).
REF 2	Bioorg Med Chem Lett. 2009 Apr 15;19(8):2172-5. Epub 2009 Mar 3.Fluorinated non-imidazole histamine H3 receptor antagonists.

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