Drug General Information
Drug ID
D09VAZ
Former ID
DNC011083
Drug Name
TRIENTINE
Drug Type
Small molecular drug
Indication Inborn error of metabolism [ICD10:E88.9] Approved [551871]
Structure
Download
2D MOL

3D MOL

Formula
C6H19ClN4
Canonical SMILES
C(CNCCNCCN)N
InChI
1S/C6H18N4/c7-1-3-9-5-6-10-4-2-8/h9-10H,1-8H2
InChIKey
VILCJCGEZXAXTO-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Carbonic anhydrase XIV Target Info Inhibitor [530998]
KEGG Pathway Nitrogen metabolism
Reactome Reversible hydration of carbon dioxide
WikiPathways Reversible Hydration of Carbon Dioxide
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 530998J Med Chem. 2010 Aug 12;53(15):5511-22.Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.

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