Drug General Information
Drug ID
D0A0FL
Former ID
DAP001229
Drug Name
Bupivacaine
Synonyms
Anekain; Bloqueina; Bucaine; Bupivacaina; Bupivacainum; Bupivan; CBupivacaine; Carbostesin; DepoBupivacaine; Marcaina; Marcaine; Sensorcaine; Bupivacaine Carbonate; Bupivacaine HCL; Bupivacaine HCL KIT; Marcaine HCL; Marcaine Spinal; AH 250; Win 11318; Win 11318 HCl; Bucaine (TN); Bupivacaina [INN-Spanish]; Bupivacaine (INN); Bupivacaine Monohydrochloride, Monohydrate; Bupivacaine [INN:BAN]; Bupivacainum [INN-Latin]; DL-Bupivacaine; DUR-843; Marcain (TN); Marcaine (TN); Sensorcaine (TN); Sensorcaine-MPF; Sensorcaine-MPFSpinal; Transdur-Bupivacaine; Vivacaine (TN); Dl-1-Butyl-2',6'-pipecoloxylidide; (+-)-Bupivacaine; (1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide; (inverted exclamation markA)-bupivacaine; 1-Butyl-2',6'-pipecoloxylidide; 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide; 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
Drug Type
Small molecular drug
Indication Anesthesia [ICD9: 338; ICD10:R20.0] Approved [538239], [539524]
Therapeutic Class
Anesthetics
Company
AstraZeneca
Structure
Download
2D MOL

3D MOL

Formula
C18H28N2O
InChI
InChI=1S/C18H28N2O/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21)
InChIKey
LEBVLXFERQHONN-UHFFFAOYSA-N
CAS Number
CAS 2180-92-9
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:3215
SuperDrug ATC ID
N01BB01
SuperDrug CAS ID
cas=038396393
Target and Pathway
Target(s) Voltage-gated sodium channel subunit alpha Nav1.8 Target Info Modulator [556264]
Reactome Interaction between L1 and Ankyrins
References
Ref 538239FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 071810.
Ref 539524(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2397).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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