Drug General Information
Drug ID	D0A0GD
Former ID	DNC002973
Drug Name	3-Hydroxy-Myristic Acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551393]
Structure		Download 2D MOL 3D MOL
Formula	C14H27O3-
Canonical SMILES	CCCCCCCCCCCC(CC(=O)[O-])O
InChI	1S/C14H28O3/c1-2-3-4-5-6-7-8-9-10-11-13(15)12-14(16)17/h13,15H,2-12H2,1H3,(H,16,17)/p-1
InChIKey	ATRNZOYKSNPPBF-UHFFFAOYSA-M
PubChem Compound ID	22053132
PubChem Substance ID	57385331, 104233836, 137183563, 223736669
Target and Pathway
Target(s)	Lymphocyte antigen 96	Target Info	Inhibitor	[551393]
	Toll-like receptor 4	Target Info	Inhibitor	[551393]
KEGG Pathway	NF-kappa B signaling pathway
	Toll-like receptor signaling pathway
	Pathogenic Escherichia coli infection
	Pertussis
	Toxoplasmosishsa04064:NF-kappa B signaling pathway
	HIF-1 signaling pathway
	Phagosome
	PI3K-Akt signaling pathway
	Salmonella infection
	Legionellosis
	Leishmaniasis
	Chagas disease (American trypanosomiasis)
	Malaria
	Toxoplasmosis
	Amoebiasis
	Tuberculosis
	Hepatitis B
	Measles
	Influenza A
	Proteoglycans in cancer
	Inflammatory bowel disease (IBD)
	Rheumatoid arthritis
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
	IL6 Signaling PathwayNetPath_17:IL5 Signaling Pathway
	IL2 Signaling Pathway
	IL4 Signaling Pathway
PANTHER Pathway	Toll receptor signaling pathwayP00054:Toll receptor signaling pathway
Pathway Interaction Database	Endogenous TLR signalingtoll_endogenous_pathway:Endogenous TLR signaling
Reactome	Ligand-dependent caspase activation
	Toll Like Receptor 4 (TLR4) Cascade
	MyD88:Mal cascade initiated on plasma membrane
	MyD88-independent TLR3/TLR4 cascade
	TRIF-mediated programmed cell death
	MyD88 deficiency (TLR2/4)
	IRAK4 deficiency (TLR2/4)
	Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
	IKK complex recruitment mediated by RIP1
	TRAF6 mediated induction of TAK1 complexR-HSA-140534:Ligand-dependent caspase activation
	TRAF6 mediated induction of TAK1 complex
WikiPathways	Toll-like receptor signaling pathway
	Toll-Like Receptors Cascades
	MyD88:Mal cascade initiated on plasma membrane
	MyD88-independent cascade
	Pathogenic Escherichia coli infection
	Regulation of toll-like receptor signaling pathwayWP75:Toll-like receptor signaling pathway
	Primary Focal Segmental Glomerulosclerosis FSGS
	Spinal Cord Injury
	Corticotropin-releasing hormone
	Regulation of toll-like receptor signaling pathway
References
Ref 551393	How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393	How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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