Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0A2BC
|
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| Former ID |
DNC008364
|
||||
| Drug Name |
JWH-385
|
||||
| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C26H44O2
|
||||
| Canonical SMILES |
CCCCCCCCC(C)(C)C1=CC=C(C=C1)C2CC(CCC2CCCO)O
|
||||
| InChI |
1S/C26H44O2/c1-4-5-6-7-8-9-18-26(2,3)23-15-12-22(13-16-23)25-20-24(28)17-14-21(25)11-10-19-27/h12-13,15-16,21,24-25,27-28H,4-11,14,17-20H2,1-3H3/t21-,24-,25-/m1/s1
|
||||
| InChIKey |
ZWVZYXMEZOIWEQ-NQHRYMMQSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cannabinoid receptor 1 | Target Info | Inhibitor | [1] | |
| Cannabinoid receptor 2 | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Rap1 signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Retrograde endocannabinoid signalinghsa04080:Neuroactive ligand-receptor interaction | |||||
| PANTHER Pathway | Endogenous cannabinoid signaling | ||||
| Pathway Interaction Database | N-cadherin signaling events | ||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
| G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors) | |||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Small Ligand GPCRs | |||||
| BDNF signaling pathway | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like | |||||
| References | |||||
| REF 1 | Bioorg Med Chem. 2008 Jan 1;16(1):322-35. Epub 2007 Sep 22.Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. | ||||
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