Drug General Information
Drug ID	D0A5JU
Former ID	DNC011260
Drug Name	Piperidine-1-carboxylic acid adamantan-2-yl ester
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[531176]
Structure		Download 2D MOL 3D MOL
Formula	C16H25NO2
Canonical SMILES	C1CCN(CC1)C(=O)OC2C3CC4CC(C3)CC2C4
InChI	1S/C16H25NO2/c18-16(17-4-2-1-3-5-17)19-15-13-7-11-6-12(9-13)10-14(15)8-11/h11-15H,1-10H2
InChIKey	VAQVMFMOXWTAGF-UHFFFAOYSA-N
PubChem Compound ID	52945668
Target and Pathway
Target(s)	Corticosteroid 11-beta-dehydrogenase, isozyme 1	Target Info	Inhibitor	[531176]
KEGG Pathway	Steroid hormone biosynthesis
	Metabolism of xenobiotics by cytochrome P450
	Metabolic pathways
	Chemical carcinogenesis
NetPath Pathway	IL1 Signaling Pathway
	FSH Signaling Pathway
PathWhiz Pathway	Steroidogenesis
Reactome	Glucocorticoid biosynthesis
WikiPathways	Prostaglandin Synthesis and Regulation
	Metabolism of steroid hormones and vitamin D
	Glucocorticoid & Mineralcorticoid Metabolism
References
Ref 531176	Bioorg Med Chem Lett. 2010 Nov 15;20(22):6725-9. Epub 2010 Sep 7.Discovery and optimization of adamantyl carbamate inhibitors of 11|A-HSD1.
Ref 531176	Bioorg Med Chem Lett. 2010 Nov 15;20(22):6725-9. Epub 2010 Sep 7.Discovery and optimization of adamantyl carbamate inhibitors of 11|A-HSD1.

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