Drug Information

Drug General Information
Drug ID
D0AK5G
Former ID
DIB003241
Drug Name
RPAF-AH
Indication Sepsis [ICD9: 995.91; ICD10:A40, A41] Discontinued in Phase 3 [521515]
Company
ICOS Corp
CAS Number
CAS 76901-00-3
Target and Pathway
Target(s) Lipoprotein-associated phospholipase A2 Target Info Modulator [546181]
KEGG Pathway Ether lipid metabolism
Metabolic pathways
Biosynthesis of antibiotics
Pathway Interaction Database Lissencephaly gene (LIS1) in neuronal migration and development
WikiPathways IL1 and megakaryotyces in obesity
Synthesis, Secretion, and Deacylation of Ghrelin
References
Ref 521515ClinicalTrials.gov (NCT00037687) Safety and Efficacy of Recombinant Human Platelet-Activating Factor Acetylhydrolase for the Treatment of Severe Sepsis. U.S. National Institutes of Health.
Ref 546181Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006777)

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