Drug General Information
Drug ID	D0AT2Z
Former ID	DNC003596
Drug Name	3-Phenylsulfanylmethyl-quinoxaline-5,7-diamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533598]
Structure		Download 2D MOL 3D MOL
Formula	C15H14N4S
Canonical SMILES	C1=CC=C(C=C1)SCC2=NC3=C(C=C(C=C3N=C2)N)N
InChI	1S/C15H14N4S/c16-10-6-13(17)15-14(7-10)18-8-11(19-15)9-20-12-4-2-1-3-5-12/h1-8H,9,16-17H2
InChIKey	PBRHNJQCRCVADQ-UHFFFAOYSA-N
PubChem Compound ID	44362450
Target and Pathway
Target(s)	Dihydrofolate reductase	Target Info	Inhibitor	[533598]
PathWhiz Pathway	Folate Metabolism
	Pterine Biosynthesis
Reactome	E2F mediated regulation of DNA replication
	Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
	Metabolism of folate and pterines
	G1/S-Specific Transcription
References
Ref 533598	J Med Chem. 1995 Nov 24;38(24):4739-59.New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.
Ref 533598	J Med Chem. 1995 Nov 24;38(24):4739-59.New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.

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