Drug Information

Drug General Information
Drug ID
D0AZ4T
Former ID
DNC000559
Drug Name
Dihydroorotate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [537699]
Structure
Download
2D MOL

3D MOL
Formula
C5H6N2O4
Canonical SMILES
C1C(NC(=O)NC1=O)C(=O)O
InChI
1S/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11)
InChIKey
UFIVEPVSAGBUSI-UHFFFAOYSA-N
CAS Number
CAS 124584-08-3
PubChem Compound ID
648
PubChem Substance ID
7723002, 8147950, 8150724, 10529020, 15243204, 24439010, 24894067, 51074268, 53788891, 57320371, 80159028, 85085441, 87245400, 91685710, 92298307, 103111954, 103274950, 104295439, 117593758, 117609103, 118239446, 125354050, 125539468, 125539521, 126523350, 129360419, 132510716, 135077112, 136995572, 137005525, 143263990, 143512009, 162089967, 162194773, 162797045, 163788444, 164787438, 169956461, 184572162, 184597045, 202820905, 204426224, 204426225, 226493331, 241124522, 242066009, 249841590, 252348685, 252351221
Target and Pathway
Target(s) Dihydroorotate dehydrogenase, mitochondrial Target Info Inhibitor [537699]
KEGG Pathway Pyrimidine metabolism
Metabolic pathways
PathWhiz Pathway Pyrimidine Metabolism
Reactome Pyrimidine biosynthesis
WikiPathways Metabolism of nucleotides
References
Ref 537699Structure-activity relationships of pyrimidines as dihydroorotate dehydrogenase inhibitors. Biochem Pharmacol. 1988 Oct 15;37(20):3807-16.
Ref 537699Structure-activity relationships of pyrimidines as dihydroorotate dehydrogenase inhibitors. Biochem Pharmacol. 1988 Oct 15;37(20):3807-16.

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