Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0AZ5V
|
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| Former ID |
DIB006723
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| Drug Name |
L-698544
|
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| Synonyms |
CNDQ
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| Drug Type |
Small molecular drug
|
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| Indication | Alzheimer disease [ICD9: 331; ICD10:G30] | Terminated | [1] | ||
| Company |
Merck & Co Inc
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C9H7ClN2O3
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| Canonical SMILES |
C1([N+](=O)[O-])C(=O)Nc2c(C1)ccc(c2)Cl
|
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| CAS Number |
CAS 147778-05-0
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Glutamate receptor AMPA subtype | Target Info | Antagonist | [2] | |
| NMDA receptor | Target Info | Modulator | [2] | ||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003218) | ||||
| REF 2 | 3-Nitro-3,4-dihydro-2(1H)-quinolones. Excitatory amino acid antagonists acting at glycine-site NMDA and (RS)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. J Med Chem. 1993 Oct 29;36(22):3397-408. | ||||
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