Drug General Information
Drug ID
D0B0EL
Former ID
DIB018859
Drug Name
AP18
Synonyms
AP-18; AP 18
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467479]
Structure
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2D MOL

3D MOL

Formula
C11H12ClNO
InChI
InChI=1S/C11H12ClNO/c1-8(9(2)13-14)7-10-3-5-11(12)6-4-10/h3-7,14H,1-2H3/b8-7+,13-9+
InChIKey
MHTJEUOFLVQMCL-NJHPPEEMSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily A member 1 Target Info Blocker (channel blocker) [529224]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 467479(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4134).
Ref 529224A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. Mol Pain. 2007 Dec 17;3:40.

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