Drug General Information
Drug ID
D0B0YD
Former ID
DNC000987
Drug Name
N-alpha-methyl histamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538752]
Structure
Download
2D MOL
Formula
C6H11N3
InChI
InChI=1S/C6H11N3/c1-7-3-2-6-4-8-5-9-6/h4-5,7H,2-3H2,1H3,(H,8,9)
InChIKey
PHSPJQZRQAJPPF-UHFFFAOYSA-N
CAS Number
CAS 673-50-7
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Histamine H4 receptor Target Info Agonist [535847]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 538752(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1239).
Ref 535847Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor. Br J Pharmacol. 2003 Nov;140(6):1117-27. Epub 2003 Oct 6.

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