Drug General Information
Drug ID	D0B9TN
Former ID	DNC010459
Drug Name	2-(2-Bromophenylthio)-N,N-dimethylethanamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530699]
Structure		Download 2D MOL 3D MOL
Formula	C10H14BrNS
Canonical SMILES	CN(C)CCSC1=CC=CC=C1Br
InChI	1S/C10H14BrNS/c1-12(2)7-8-13-10-6-4-3-5-9(10)11/h3-6H,7-8H2,1-2H3
InChIKey	WXAWOWHEHSIUMN-UHFFFAOYSA-N
PubChem Compound ID	46233353
Target and Pathway
Target(s)	5-hydroxytryptamine 7 receptor	Target Info	Inhibitor	[530699]
KEGG Pathway	Ras signaling pathway
	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome	Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 530699	Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. Epub 2010 Jan 18.SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling.
Ref 530699	Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. Epub 2010 Jan 18.SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.