Drug Information

Drug General Information
Drug ID
D0BH2T
Former ID
DNC013340
Drug Name
2,2',4,4'-tetrahydroxychalcone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528649]
Structure
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2D MOL

3D MOL
Formula
C15H12O5
Canonical SMILES
C1=CC(=C(C=C1O)O)C=CC(=O)C2=C(C=C(C=C2)O)O
InChI
1S/C15H12O5/c16-10-3-1-9(14(19)7-10)2-6-13(18)12-5-4-11(17)8-15(12)20/h1-8,16-17,19-20H/b6-2+
InChIKey
ZWTDXYUDJYDHJR-QHHAFSJGSA-N
PubChem Compound ID
10107266
Target and Pathway
Target(s) Tyrosine oxidase Target Info Inhibitor [528649]
BioCyc Pathway (S)-reticuline biosynthesis
Eumelanin biosynthesis
L-dopachrome biosynthesis
KEGG Pathway Tyrosine metabolism
Riboflavin metabolism
Metabolic pathways
Melanogenesis
PathWhiz Pathway Riboflavin Metabolism
Tyrosine Metabolism
WikiPathways Dopamine metabolism
References
Ref 528649Bioorg Med Chem. 2007 Mar 15;15(6):2396-402. Epub 2007 Jan 17.Synthesis and evaluation of 2',4',6'-trihydroxychalcones as a new class of tyrosinase inhibitors.
Ref 528649Bioorg Med Chem. 2007 Mar 15;15(6):2396-402. Epub 2007 Jan 17.Synthesis and evaluation of 2',4',6'-trihydroxychalcones as a new class of tyrosinase inhibitors.

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