Drug Information

Drug General Information
Drug ID
D0C1EF
Former ID
DNC002966
Drug Name
5-(4-Methoxyphenoxy)-2,4-Quinazolinediamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C15H14N4O2
Canonical SMILES
COC1=CC=C(C=C1)OC2=CC=CC3=C2C(=NC(=N3)N)N
InChI
1S/C15H14N4O2/c1-20-9-5-7-10(8-6-9)21-12-4-2-3-11-13(12)14(16)19-15(17)18-11/h2-8H,1H3,(H4,16,17,18,19)
InChIKey
CPZJZAIZIMCJRC-UHFFFAOYSA-N
PubChem Compound ID
447098
PubChem Substance ID
826355, 7678026, 7889026, 36889342, 46508061, 52115157, 104637494, 127661058, 136883739, 137184716, 142351642, 160965595, 228265045
Target and Pathway
Target(s) Dihydrofolate reductase Target Info Inhibitor [551393]
PathWhiz Pathway Folate Metabolism
Pterine Biosynthesis
Reactome E2F mediated regulation of DNA replication
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Metabolism of folate and pterines
G1/S-Specific Transcription
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.