Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0C2HR
|
||||
Former ID |
DIB014459
|
||||
Drug Name |
ORG-9273
|
||||
Synonyms |
1-[(2beta,3alpha,5alpha,16beta,17beta)-17-Acetoxy-3-hydroxy-2-morpholinoandrostan-16-yl]-1-methylpiperidinium bromide; 17beta-Acetoxy-3alpha-hydroxy-16beta-(1-methylhexahydropyridinio-1-yl)-2beta-morpholino-5alpha-androstane bromide
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Paralysis [ICD10:G72.3] | Discontinued in Phase 2 | [528223] | ||
Structure |
Download2D MOL |
||||
Formula |
C31H53N2O4+
|
||||
Canonical SMILES |
CC(=O)OC1C(CC2C1(CCC3C2CCC4C3(CC(C(C4)O)N5CCOCC5)C)C)[N<br />+]6(CCCCC6)C
|
||||
InChI |
1S/C31H53N2O4/c1-21(34)37-29-27(33(4)14-6-5-7-15-33)19-25-23-9-8-22-18-28(35)26(32-12-16-36-17-13-32)20-31(22,3)24(23)10-11-30(25,29)2/h22-29,35H,5-20H2,1-4H3/q+1/t22-,23?,24?,25?,26-,27-,28-,29-,30-,31-/m0/s1
|
||||
InChIKey |
DHYOZTTVCWLBTR-JHKQNVCFSA-N
|
||||
PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Nicotinic acetylcholine receptor | Target Info | Modulator | [528223], [551871] | |
References | |||||
Ref 528223 | Dose-response relation, neuromuscular blocking action, intubation conditions, and cardiovascular effects of Org 9273, a new neuromuscular blocking agent. Anesth Analg. 1991 Jun;72(6):811-6. | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.