Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0C8MT
|
||||
| Former ID |
DNC009584
|
||||
| Drug Name |
2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C17H18N2O
|
||||
| Canonical SMILES |
C1=CC=C(C=C1)COC2=CC=CC3=C2NC=C3CCN
|
||||
| InChI |
1S/C17H18N2O/c18-10-9-14-11-19-17-15(14)7-4-8-16(17)20-12-13-5-2-1-3-6-13/h1-8,11,19H,9-10,12,18H2
|
||||
| InChIKey |
JOYGWYISRWPUIM-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Leukotriene A-4 hydrolase | Target Info | Inhibitor | [2] | |
| TRPM8 protein | Target Info | Inhibitor | [1] | ||
| BioCyc Pathway | Leukotriene biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathwayshsa04750:Inflammatory mediator regulation of TRP channels | |||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| Reactome | TRP channels | ||||
| WikiPathways | Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2010 Dec 1;20(23):7076-9. Epub 2010 Sep 22.5-benzyloxytryptamine as an antagonist of TRPM8. | ||||
| REF 2 | J Med Chem. 2008 Dec 25;51(24):7882-8.Discovery of multitarget inhibitors by combining molecular docking with common pharmacophore matching. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.