Drug Information

Drug General Information
Drug ID
D0D1ON
Former ID
DNC002615
Drug Name
Sri-9662
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
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2D MOL

3D MOL
Formula
C18H19N5O2
Canonical SMILES
CC1=C2C(=NC(=NC2=NC=C1C=CC3=C(C=CC(=C3)OC)OC)N)N
InChI
1S/C18H19N5O2/c1-10-12(9-21-17-15(10)16(19)22-18(20)23-17)5-4-11-8-13(24-2)6-7-14(11)25-3/h4-9H,1-3H3,(H4,19,20,21,22,23)/b5-4-
InChIKey
WNDJHUNKXPAREB-PLNGDYQASA-N
PubChem Compound ID
446753
PubChem Substance ID
824485, 7888650, 10299949, 15697277, 36889096, 46392372, 46506463, 50560270, 57404764, 104636984, 137183589, 160966211
Target and Pathway
Target(s) Dihydrofolate reductase Target Info Inhibitor [551393]
PathWhiz Pathway Folate Metabolism
Pterine Biosynthesis
Reactome E2F mediated regulation of DNA replication
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Metabolism of folate and pterines
G1/S-Specific Transcription
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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