Drug Information

Drug General Information
Drug ID
D0D6OH
Former ID
DIB018265
Drug Name
[3H]CP55940
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542363]
Structure
Download
2D MOL

3D MOL
Formula
C24H40O3
InChI
InChI=1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1
InChIKey
YNZFFALZMRAPHQ-SYYKKAFVSA-N
PubChem Compound ID
104895
PubChem Substance ID
10233661, 11110912, 14926865, 16501872, 17404752, 24278295, 44434471, 47424229, 48169362, 48393922, 50005506, 50104663, 50104664, 50628872, 53777295, 56463013, 57309818, 57337899, 71753421, 90340634, 92303455, 103112294, 103685290, 103966377, 104373169, 113635234, 117557366, 124749526, 124801426, 124886958, 126684044, 129823211, 134343221, 135061075, 135650130, 135651145, 137125085, 142472549, 162247816, 163564143, 164757773, 170481107, 223682617, 226492016, 241182008, 241377543, 250108652, 252457543, 252823772
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Agonist [534133]
G-protein coupled receptor 55 Target Info Agonist [529051]
Cannabinoid receptor 1 Target Info Agonist [534130]
KEGG Pathway Neuroactive ligand-receptor interactionhsa04015:Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signalingWP1825:GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
BDNF signaling pathway
GPCRs, Other
References
Ref 542363(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 734).
Ref 529051The orphan receptor GPR55 is a novel cannabinoid receptor. Br J Pharmacol. 2007 Dec;152(7):1092-101. Epub 2007 Sep 17.
Ref 534130Structural features of the central cannabinoid CB1 receptor involved in the binding of the specific CB1 antagonist SR 141716A. J Biol Chem. 1996 Mar 22;271(12):6941-6.
Ref 534133Signaling pathway associated with stimulation of CB2 peripheral cannabinoid receptor. Involvement of both mitogen-activated protein kinase and induction of Krox-24 expression. Eur J Biochem. 1996 May1;237(3):704-11.

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