Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0DC6U
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| Former ID |
DCL000765
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| Drug Name |
Dapivirine
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| Synonyms |
Dapivirinum; R 147681; R147681; TMC 120; TMC120; GEL-002; R-147681; TMC-120; TMC120-R147681; TMC-120/R-147681; 4-((4-((2,4,6-Trimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile; 4-({4-[(2,4,6-Trimethylphenyl)amino]pyrimidin-2-yl}amino)benzenecarbonitrile; 4-[4-(2,4,6-TRIMETHYL-PHENYLAMINO)-PYRIMIDIN-2-YLAMINO]-BENZONITRILE; 4-[[4-(2,4,6-trimethylanilino)pyrimidin-2-yl]amino]benzonitrile
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| Drug Type |
Small molecular drug
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| Indication | Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] | Phase 1/2 | [536833] | ||
| Company |
International Partnership for Microbicides, Inc.
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| Structure |
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Download2D MOL |
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| Formula |
C20H19N5
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| Canonical SMILES |
CC1=CC(=C(C(=C1)C)NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C
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| InChI |
1S/C20H19N5/c1-13-10-14(2)19(15(3)11-13)24-18-8-9-22-20(25-18)23-17-6-4-16(12-21)5-7-17/h4-11H,1-3H3,(H2,22,23,24,25)
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| InChIKey |
ILAYIAGXTHKHNT-UHFFFAOYSA-N
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| CAS Number |
CAS 244767-67-7
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| PubChem Compound ID | |||||
| PubChem Substance ID |
642581, 832334, 7890844, 9371781, 14826606, 30418382, 57304387, 57399694, 58107209, 74755470, 87360616, 99445110, 103269662, 103819222, 113456437, 117514641, 118310899, 128183411, 134339251, 135129476, 137098215, 139360977, 160969668, 162009845, 162011984, 162205059, 163658445, 164838828, 172096442, 196408561, 198967137, 210275071, 210280709, 219070854, 223404305, 223485471, 223738760, 226714093, 242060328, 252125394, 252160229, 252215246, 252435536, 252450480
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| Target and Pathway | |||||
| Target(s) | HIV-1 reverse transcriptase | Target Info | Inhibitor | [536833] | |
| References | |||||
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