Drug Information

Drug General Information
Drug ID
D0DM5A
Former ID
DIB014407
Drug Name
SIM-6080
Synonyms
N1,N2-Dimethyl-N1-[3,3-di(4-fluorophenyl)propyl]-N2-(3,4,5-trimethoxybenzyl)ethylenediamine
Drug Type
Small molecular drug
Indication Angina pectoris [ICD9: 413; ICD10:I20] Terminated [544566]
Structure
Download
2D MOL

3D MOL
Formula
C29H36F2N2O3
Canonical SMILES
CN(CCC(C1=CC=C(C=C1)F)C2=CC=C(C=C2)F)CCN(C)CC3=CC(=C(C(<br />=C3)OC)OC)OC
InChI
1S/C29H36F2N2O3/c1-32(16-17-33(2)20-21-18-27(34-3)29(36-5)28(19-21)35-4)15-14-26(22-6-10-24(30)11-7-22)23-8-12-25(31)13-9-23/h6-13,18-19,26H,14-17,20H2,1-5H3
InChIKey
NOMSFNRBXCWAIE-UHFFFAOYSA-N
PubChem Compound ID
602534
PubChem Substance ID
8694334, 15333139, 43161939, 57406987, 76210749, 113515636, 135227447, 232901111, 250060369
Target and Pathway
Target(s) Calcium channel Target Info Blocker [534236], [551871]
References
Ref 544566Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000149)
Ref 534236Determination of the calcium antagonist SIM6080 and its N- and O-demethylated metabolites in plasma, urine and tissues by high-performance liquid chromatography. J Chromatogr B Biomed Appl. 1996 Feb 9;676(1):77-85.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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