Drug Information
Drug General Information | |||||
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Drug ID |
D0DQ3F
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Former ID |
DNC006995
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Drug Name |
JWH-365
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
Download2D MOL |
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Formula |
C28H29NO
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Canonical SMILES |
CCCCCN1C=C(C=C1C2=CC=CC=C2CC)C(=O)C3=CC=CC4=CC=CC=C43
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InChI |
1S/C28H29NO/c1-3-5-10-18-29-20-23(19-27(29)25-16-9-6-12-21(25)4-2)28(30)26-17-11-14-22-13-7-8-15-24(22)26/h6-9,11-17,19-20H,3-5,10,18H2,1-2H3
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InChIKey |
SNWJCZXZSGPAJM-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Cannabinoid receptor 1 | Target Info | Inhibitor | [1] | |
Cannabinoid receptor 2 | Target Info | Inhibitor | [1] | ||
KEGG Pathway | Rap1 signaling pathway | ||||
Neuroactive ligand-receptor interaction | |||||
Retrograde endocannabinoid signalinghsa04080:Neuroactive ligand-receptor interaction | |||||
PANTHER Pathway | Endogenous cannabinoid signaling | ||||
Pathway Interaction Database | N-cadherin signaling events | ||||
Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors) | |||||
G alpha (i) signalling events | |||||
WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
Small Ligand GPCRs | |||||
BDNF signaling pathway | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like | |||||
References | |||||
REF 1 | Bioorg Med Chem Lett. 2006 Oct 15;16(20):5432-5. Epub 2006 Aug 4.1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors. | ||||
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