Drug Information

Drug General Information
Drug ID
D0DQ6Z
Former ID
DNC000027
Drug Name
1,4-Naphthoquinone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534955]
Structure
Download
2D MOL

3D MOL
Formula
C10H6O2
Canonical SMILES
C1=CC=C2C(=O)C=CC(=O)C2=C1
InChI
1S/C10H6O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6H
InChIKey
FRASJONUBLZVQX-UHFFFAOYSA-N
CAS Number
CAS 130-15-4
PubChem Compound ID
8530
PubChem Substance ID
5602, 75035, 588830, 600877, 3136613, 5943270, 8139885, 8156025, 10506347, 10852286, 11371688, 11374908, 11484077, 11488297, 11490570, 11493059, 12055864, 14793918, 17425041, 24849257, 26679313, 26757484, 29204424, 29227205, 32581857, 38374893, 48259572, 49996619, 50111628, 53787433, 56269727, 56370075, 57325077, 57390733, 77852366, 85247019, 87573450, 88811914, 93618177, 102851577, 103240920, 103811485, 104318097, 109454404, 117586811, 124637355, 125275433, 125339839, 126545966, 126677177
ChEBI ID
ChEBI:27418
Target and Pathway
Target(s) Dihydroorotate dehydrogenase, mitochondrial Target Info Inhibitor [534955]
KEGG Pathway Pyrimidine metabolism
Metabolic pathways
PathWhiz Pathway Pyrimidine Metabolism
Reactome Pyrimidine biosynthesis
WikiPathways Metabolism of nucleotides
References
Ref 534955Kinetics of inhibition of human and rat dihydroorotate dehydrogenase by atovaquone, lawsone derivatives, brequinar sodium and polyporic acid. Chem Biol Interact. 2000 Jan 3;124(1):61-76.
Ref 534955Kinetics of inhibition of human and rat dihydroorotate dehydrogenase by atovaquone, lawsone derivatives, brequinar sodium and polyporic acid. Chem Biol Interact. 2000 Jan 3;124(1):61-76.

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