Drug General Information
Drug ID
D0E2LH
Former ID
DIB011841
Drug Name
TT-173
Indication Bleeding [ICD9: 444, 453; ICD10:I74, I80-I82] Phase 2 [524568]
Company
Thrombotargets
Target and Pathway
Target(s) Tissue factor Target Info Modulator [533319]
KEGG Pathway Complement and coagulation cascades
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
TWEAK Signaling Pathway
PANTHER Pathway Angiogenesis
Blood coagulation
PathWhiz Pathway Coagulation
Reactome Extrinsic Pathway of Fibrin Clot Formation
WikiPathways Complement and Coagulation Cascades
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 524568ClinicalTrials.gov (NCT02012569) Determine the Haemostatic Efficacy of TT-173, Reducing the Bleeding Time in the Donor Site of Skin Grafting. U.S. National Institutes of Health.
Ref 533319TETIS study: evaluation of new topical hemostatic agent TT-173 in tooth extraction. Clin Oral Investig. 2015 Sep 15.

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