Drug General Information |
Drug ID |
D0E3KD
|
Former ID |
DNC002875
|
Drug Name |
9-(4-Hydroxyphenyl)-2,7-Phenanthroline
|
Drug Type |
Small molecular drug
|
Indication |
Discovery agent
|
Investigative |
[1]
|
Structure |
|
Download
2D MOL
3D MOL
|
Formula |
C18H12N2O
|
Canonical SMILES |
C1=CC(=O)C=CC1=C2C=C3C(=CC=C4C3=CNC=C4)N=C2
|
InChI |
1S/C18H12N2O/c21-15-4-1-12(2-5-15)14-9-16-17-11-19-8-7-13(17)3-6-18(16)20-10-14/h1-11,19H
|
InChIKey |
LQCQDYRLKBYBNB-UHFFFAOYSA-N
|
PubChem Compound ID |
|
PubChem Substance ID |
829652, 7885567, 34951423, 39299528, 46392886, 46507868, 46516286, 53696368, 103554408, 113905037, 137184963, 160966723, 180398207, 230251233, 245720424
|
Target and Pathway |
Target(s) |
Mitogen-activated protein kinase 10 |
Target Info |
Inhibitor |
[1]
|
KEGG Pathway
|
MAPK signaling pathway
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ErbB signaling pathway
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Ras signaling pathway
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cAMP signaling pathway
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FoxO signaling pathway
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Sphingolipid signaling pathway
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Protein processing in endoplasmic reticulum
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Wnt signaling pathway
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Osteoclast differentiation
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Focal adhesion
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Toll-like receptor signaling pathway
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NOD-like receptor signaling pathway
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RIG-I-like receptor signaling pathway
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Fc epsilon RI signaling pathway
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TNF signaling pathway
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Neurotrophin signaling pathway
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Retrograde endocannabinoid signaling
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Dopaminergic synapse
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Inflammatory mediator regulation of TRP channels
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Insulin signaling pathway
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GnRH signaling pathway
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Progesterone-mediated oocyte maturation
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Prolactin signaling pathway
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Adipocytokine signaling pathway
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Type II diabetes mellitus
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Non-alcoholic fatty liver disease (NAFLD)
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Epithelial cell signaling in Helicobacter pylori infection
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Shigellosis
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Salmonella infection
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Pertussis
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Chagas disease (American trypanosomiasis)
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Toxoplasmosis
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Tuberculosis
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Hepatitis C
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Hepatitis B
|
Influenza A
|
Herpes simplex infection
|
Epstein-Barr virus infection
|
Pathways in cancer
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Colorectal cancer
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Pancreatic cancer
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Choline metabolism in cancer
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PANTHER Pathway
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Alzheimer disease-amyloid secretase pathway
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Apoptosis signaling pathway
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B cell activation
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EGF receptor signaling pathway
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FAS signaling pathway
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FGF signaling pathway
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Integrin signalling pathway
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Interferon-gamma signaling pathway
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Parkinson disease
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TGF-beta signaling pathway
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Ras Pathway
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CCKR signaling map ST
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Pathway Interaction Database
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Noncanonical Wnt signaling pathway
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CD40/CD40L signaling
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FAS (CD95) signaling pathway
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Glucocorticoid receptor regulatory network
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FoxO family signaling
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p75(NTR)-mediated signaling
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ErbB2/ErbB3 signaling events
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PDGFR-beta signaling pathway
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Nephrin/Neph1 signaling in the kidney podocyte
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Reactome
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Oxidative Stress Induced Senescence
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FCERI mediated MAPK activation
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JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
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Activation of the AP-1 family of transcription factors
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WikiPathways
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Toll-like receptor signaling pathway
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DNA Damage Response (only ATM dependent)
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G13 Signaling Pathway
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Insulin Signaling
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Wnt Signaling Pathway
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MAPK Cascade
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Oxidative Stress
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Wnt Signaling Pathway and Pluripotency
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Apoptosis Modulation by HSP70
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MAPK Signaling Pathway
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Nanoparticle-mediated activation of receptor signaling
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Structural Pathway of Interleukin 1 (IL-1)
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Apoptosis
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BDNF signaling pathway
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Integrin-mediated Cell Adhesion
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Regulation of toll-like receptor signaling pathway
|
References |
REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |