Drug Information

Drug General Information
Drug ID
D0E4ON
Former ID
DNC008169
Drug Name
N-butyl-4-methyl-3,4-dihydroquinazolin-2-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529158]
Structure
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2D MOL

3D MOL
Formula
C13H19N3
Canonical SMILES
CCCCNC1=NC(C2=CC=CC=C2N1)C
InChI
1S/C13H19N3/c1-3-4-9-14-13-15-10(2)11-7-5-6-8-12(11)16-13/h5-8,10H,3-4,9H2,1-2H3,(H2,14,15,16)
InChIKey
GRYGBTWCDTXWJO-UHFFFAOYSA-N
PubChem Compound ID
44456426
Target and Pathway
Target(s) 5-hydroxytryptamine 5A receptor Target Info Inhibitor [529158]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 529158Bioorg Med Chem Lett. 2008 Jan 1;18(1):262-6. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: optimising brain penetration.
Ref 529158Bioorg Med Chem Lett. 2008 Jan 1;18(1):262-6. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: optimising brain penetration.

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