Drug Information
Drug General Information | |||||
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Drug ID |
D0E4ON
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Former ID |
DNC008169
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Drug Name |
N-butyl-4-methyl-3,4-dihydroquinazolin-2-amine
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C13H19N3
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Canonical SMILES |
CCCCNC1=NC(C2=CC=CC=C2N1)C
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InChI |
1S/C13H19N3/c1-3-4-9-14-13-15-10(2)11-7-5-6-8-12(11)16-13/h5-8,10H,3-4,9H2,1-2H3,(H2,14,15,16)
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InChIKey |
GRYGBTWCDTXWJO-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | 5-hydroxytryptamine 5A receptor | Target Info | Inhibitor | [1] | |
KEGG Pathway | Calcium signaling pathway | ||||
Neuroactive ligand-receptor interaction | |||||
Serotonergic synapse | |||||
PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
Reactome | Serotonin receptors | ||||
G alpha (i) signalling events | |||||
WikiPathways | Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
References | |||||
REF 1 | Bioorg Med Chem Lett. 2008 Jan 1;18(1):262-6. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: optimising brain penetration. | ||||
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