Drug Information
Drug General Information | |||||
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Drug ID |
D0E5VP
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Former ID |
DIB006234
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Drug Name |
KF-66490
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Synonyms |
K-34; KF-66490; PDE 4 inhibitors (dermatitis/rheumatoid arthritis); PDE 4 inhibitors (dermatitis/rheumatoid arthritis), Kyowa Hakko Kirin
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Drug Type |
Small molecular drug
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Indication | Atopic dermatitis [ICD9: 691.8, 692.9; ICD10:L00-L99] | Investigative | [529747] | ||
Company |
Kyowa Hakko Kirin Co Ltd
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Structure |
Download2D MOL |
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Formula |
C18H22N4O5
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Canonical SMILES |
CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N5CC5)OC)N4C)N
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InChI |
1S/C18H22N4O5/c1-8-12(19)15(24)11-9(7-27-17(25)21-4-5-21)18(26-3)16-10(20(16)2)6-22(18)13(11)14(8)23/h9-10,16H,4-7,19H2,1-3H3
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InChIKey |
FZLZUGFFXNJCRD-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | CAMP-specific 3',5'-cyclic phosphodiesterase 4A | Target Info | Inhibitor | [529747] | |
CAMP-specific 3',5'-cyclic phosphodiesterase 4B | Target Info | Inhibitor | [529747] | ||
Type IV phosphodiesterase | Target Info | Inhibitor | [529747] | ||
NetPath Pathway | IL5 Signaling Pathway | ||||
IL2 Signaling Pathway | |||||
PathWhiz Pathway | Purine Metabolism | ||||
References |
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