Drug Information
Drug General Information | |||||
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Drug ID |
D0E9EE
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Former ID |
DCL000232
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Drug Name |
SR 144190
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Synonyms |
SR-144190; 3-(1-(2-(4-benzoyl-2-(3,4-difluorophenyl)morpholin-2-yl)ethyl)-4-phenylpiperidin-4-yl)-1-dimethylurea
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Drug Type |
Small molecular drug
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Indication | Depression; Acute or chronic pain; Anxiety disorders; Urinary incontinence [ICD9: 300, 311, 338, 338.2, 787.6, 788.3,780; ICD10:F30-F42, N39.3-N39.4, G89] | Discontinued in Phase 1 | [546499] | ||
Therapeutic Class |
Analgesics
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Company |
Sanofi-aventis
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Structure |
Download2D MOL |
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Formula |
C33H38F2N4O3
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Canonical SMILES |
CN(C)C(=O)NC1(CCN(CC1)CCC2(CN(CCO2)C(=O)C3=CC=CC=C3)C4=<br />CC(=C(C=C4)F)F)C5=CC=CC=C5
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InChI |
1S/C33H38F2N4O3/c1-37(2)31(41)36-32(26-11-7-4-8-12-26)15-18-38(19-16-32)20-17-33(27-13-14-28(34)29(35)23-27)24-39(21-22-42-33)30(40)25-9-5-3-6-10-25/h3-14,23H,15-22,24H2,1-2H3,(H,36,41)
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InChIKey |
QNLIUVLFRVYNCV-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | NK-2 receptor | Target Info | Antagonist | [535777], [535994] | |
Reactome | G alpha (q) signalling events | ||||
References |
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