Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0EK1C
|
||||
| Former ID |
DIB015750
|
||||
| Drug Name |
PHE-377
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Phase 1 | [1] | ||
| Company |
PharmEste SRL
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C16H27ClN2O
|
||||
| Canonical SMILES |
CC1=C(C(=CC=C1)C)NC(=O)C[NH+](C(C)C)C(C)C.[Cl-]
|
||||
| InChIKey |
OJTPHJHZGWBMET-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Vanilloid receptor 1 | Target Info | Antagonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Inflammatory mediator regulation of TRP channels | |||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | ||||
| Trk receptor signaling mediated by PI3K and PLC-gamma | |||||
| Reactome | TRP channels | ||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031648) | ||||
| REF 2 | Clinical pipeline report, company report or official report of Pharmeste. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.