Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0F1UZ
|
||||
| Former ID |
DCL000696
|
||||
| Drug Name |
Amitriptyline+ketamine
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Neuropathic pain [ICD9: 356.0, 356.8; ICD10:G64, G90.0] | Phase 3 | [1] | ||
| Therapeutic Class |
Analgesics
|
||||
| Company |
EpiCept Pharmaceuticals
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C20H17ClN4O2S
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | NMDA receptor | Target Info | Antagonist | [2] | |
| References | |||||
| REF 1 | A Phase III Randomized, Placebo-Controlled Study of Topical Amitriptyline and Ketamine for Chemotherapy-Induced Peripheral Neuropathy (CIPN): A University of Rochester CCOP Study of 462 Cancer Survivors. Support Care Cancer. 2014 July; 22(7): 1807-1814. | ||||
| REF 2 | Emerging drugs in neuropathic pain. Expert Opin Emerg Drugs. 2007 Mar;12(1):113-26. | ||||
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