Drug General Information
Drug ID	D0F1VR
Former ID	DNC005189
Drug Name	3,4-Dibromo-2-(5-bromo-2-hydroxy-phenoxy)-phenol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527145]
Structure		Download 2D MOL 3D MOL
Formula	C12H7Br3O3
Canonical SMILES	C1=CC(=C(C=C1Br)OC2=C(C=CC(=C2Br)Br)O)O
InChI	1S/C12H7Br3O3/c13-6-1-3-8(16)10(5-6)18-12-9(17)4-2-7(14)11(12)15/h1-5,16-17H
InChIKey	MQTQEJZMDKSDNZ-UHFFFAOYSA-N
PubChem Compound ID	44396194
Target and Pathway
Target(s)	Arachidonate 15-lipoxygenase	Target Info	Inhibitor	[527145]
BioCyc Pathway	Resolvin D biosynthesis
	Lipoxin biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Linoleic acid metabolism
	Metabolic pathways
	Serotonergic synapse
NetPath Pathway	IL4 Signaling Pathway
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database	IL4-mediated signaling events
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Arachidonic acid metabolism
	Eicosanoid Synthesis
References
Ref 527145	J Med Chem. 2004 Jul 29;47(16):4060-5.Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase.
Ref 527145	J Med Chem. 2004 Jul 29;47(16):4060-5.Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase.

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