Drug General Information
Drug ID
D0FF0Z
Former ID
DNC008912
Drug Name
4-(3-Phenylethynyl-benzyl)-1H-imidazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529437]
Structure
Download
2D MOL

3D MOL

Formula
C18H14N2
Canonical SMILES
C1=CC=C(C=C1)C#CC2=CC(=CC=C2)CC3=CN=CN3
InChI
1S/C18H14N2/c1-2-5-15(6-3-1)9-10-16-7-4-8-17(11-16)12-18-13-19-14-20-18/h1-8,11,13-14H,12H2,(H,19,20)
InChIKey
VIPAIZRIFZFESY-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Cytochrome P450 2D6 Target Info Inhibitor [529437]
KEGG Pathway Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Serotonergic synapse
Reactome Xenobiotics
WikiPathways Metapathway biotransformation
Tamoxifen metabolism
Oxidation by Cytochrome P450
Vitamin D Receptor Pathway
Aripiprazole Metabolic Pathway
Fatty Acid Omega Oxidation
Codeine and Morphine Metabolism
References
Ref 529437J Med Chem. 2008 May 22;51(10):2944-53. Epub 2008 Apr 24.4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists.
Ref 529437J Med Chem. 2008 May 22;51(10):2944-53. Epub 2008 Apr 24.4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists.

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