Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0FW8K
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| Former ID |
DIB018093
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| Drug Name |
(RS)-(tetrazol-5-yl)glycine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [540662] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C3H5N5O2
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| InChI |
InChI=1S/C3H5N5O2/c4-1(3(9)10)2-5-7-8-6-2/h1H,4H2,(H,9,10)(H,5,6,7,8)
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| InChIKey |
UKBRUIZWQZHXFL-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID |
586327, 5875704, 10241565, 14747786, 26751673, 29305961, 47288893, 48108210, 57341752, 75313533, 103382586, 104363527, 129379692, 132555109, 135083408, 137237459, 140384326, 162022557, 162224105, 178100891, 184592734, 189614594, 204430833, 219605028, 223442265, 235546155, 241033794, 241181612, 246265494
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| Target and Pathway | |||||
| Target(s) | Glutamate [NMDA] receptor subunit epsilon 1 | Target Info | Agonist | [543837] | |
| GluN2D | Target Info | Agonist | [543840] | ||
| NMDA receptor subunit NR1 | Target Info | Agonist | [543836] | ||
| Glutamate [NMDA] receptor subunit epsilon 2 | Target Info | Agonist | [543838] | ||
| GluN2C | Target Info | Agonist | [543839] | ||
| KEGG Pathway | Ras signaling pathway | ||||
| Rap1 signaling pathway | |||||
| Calcium signaling pathway | |||||
| cAMP signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| Circadian entrainment | |||||
| Long-term potentiation | |||||
| Glutamatergic synapse | |||||
| Dopaminergic synapse | |||||
| Alzheimer's disease | |||||
| Amyotrophic lateral sclerosis (ALS) | |||||
| Cocaine addiction | |||||
| Amphetamine addiction | |||||
| Nicotine addiction | |||||
| Alcoholism | |||||
| Systemic lupus erythematosushsa04014:Ras signaling pathway | |||||
| Huntington's disease | |||||
| Alcoholismhsa04014:Ras signaling pathway | |||||
| Systemic lupus erythematosus | |||||
| PANTHER Pathway | Huntington disease | ||||
| Ionotropic glutamate receptor pathway | |||||
| Metabotropic glutamate receptor group III pathway | |||||
| Metabotropic glutamate receptor group I pathway | |||||
| Muscarinic acetylcholine receptor 1 and 3 signaling pathwayP00029:Huntington disease | |||||
| Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||||
| Pathway Interaction Database | Reelin signaling pathwayerbb4_pathway:ErbB4 signaling events | ||||
| Reelin signaling pathway | |||||
| References | |||||
| Ref 543836 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 455). | ||||
| Ref 543837 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 456). | ||||
| Ref 543838 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 457). | ||||
| Ref 543839 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 458). | ||||
| Ref 543840 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 459). | ||||
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